Which of the following medications is indicated for the management of constipation?

Colace, also known as docusate sodium, is a stool softener that is specifically indicated for the management of constipation. It works by increasing the amount of water in the stool, making it easier to pass. This mechanism helps individuals who may be experiencing constipation due to various reasons, including dietary habits, dehydration, or the use of certain medications that can lead to hard stools.

In contrast, Imodium (loperamide) is primarily used to treat diarrhea by slowing down gut movement. MS Contin (morphine sulfate) is a medication for pain management and can often cause constipation as a side effect. Nexium (esomeprazole) is a proton pump inhibitor used to treat gastrointestinal reflux diseases, rather than being indicated for constipation. Therefore, Colace is the appropriate choice for the management of constipation.