Which medication is classified as a second-generation antihistamine?

Fexofenadine is classified as a second-generation antihistamine, which means it is designed to specifically target allergic symptoms while minimizing sedation. Second-generation antihistamines, such as fexofenadine, are developed to have less penetration into the central nervous system compared to first-generation antihistamines. This reduced ability to cross the blood-brain barrier leads to fewer sedative effects, making them more suitable for use during the day when alertness is necessary.

In contrast, first-generation antihistamines, like diphenhydramine, are associated with more drowsiness and sedation. Salmeterol and albuterol are not antihistamines; they are bronchodilators used for asthma and COPD management. This distinction is critical because it highlights the specific therapeutic uses and side effects related to each class of medication, emphasizing the importance of selecting the right medication based on the patient’s condition and the desired outcomes.