What type of interaction must be assessed during the prospective drug utilization review?

The assessment of drug-drug interactions during the prospective drug utilization review is crucial in ensuring patient safety and effective therapy management. This review process involves evaluating a patient's medication regimen before dispensing a new prescription or adjusting dosages.

Drug-drug interactions occur when two or more medications react with each other, potentially leading to diminished therapeutic effects or increased adverse effects. These interactions can affect the metabolism, absorption, or excretion of drugs, which can significantly impact patient outcomes. For instance, certain medications may inhibit or induce metabolic enzymes, altering the expected concentration of a drug in the bloodstream, which can lead to toxicity or therapeutic failure.

Identifying potential drug-drug interactions allows pharmacy technicians to alert pharmacists so they can take necessary actions, such as adjusting dosages, switching medications, or counseling patients on the risks involved. This proactive approach is essential in minimizing risks and maximizing the safety and efficacy of pharmacotherapy.

Other types of interactions, while important, may not be the primary focus of a routine prospective drug utilization review. Food-drug interactions, for instance, concern the effects of certain foods on drug absorption and effectiveness. Genetic interactions involve variations in drug response based on an individual’s genetic makeup, while pediatric interactions focus on medication considerations specific to children. Though these considerations